Everyone has a love of beauty. We all want our faces to be smooth and white, but many women will have different degrees of spots after 30. There are many reasons for the formation of spots, such as sun exposure, endocrine, excessive work pressure, etc. first of all, to cover up the spots on your face, you use freckle cream, isolation cream, etc. the best way is to treat them fundamentally. Some freckle cream makes the spots more serious because of its poor permeability. Let’s take a look at the methods of freckle removal
1. Hydroquinone
Similar to the substrate tyrosine of tyrosinase, it can competitively inhibit the activity of tyrosinase and affect the formation of melanin. The mechanism of action of hydroquinone also includes inhibiting DNA and RNA complexes, denuding melanosomes and destroying melanocytes, thus promoting the decomposition of melanosomes. The efficacy of hydroquinone is related to its concentration, matrix and chemical stability of the product. The higher the concentration, the better the treatment effect and the greater the irritation. The commonly used concentration is 2% ~ 5%. The common method of hydroquinone is external use twice a day. Generally, the skin color becomes lighter after 4 weeks, and the best effect is obtained after 6 to 10 weeks. If broad-spectrum sunscreen is applied in combination during the day, the efficacy of hydroquinone can be improved. However, long-term use of Hydroquinone at a concentration of 4% ~ 5% can cause primary irritation, contact dermatitis and post-inflammatory pigmentation, as well as exogenous melatonin and skin darkening. 2% hydroquinone combined with 0.05% or 0.1% retinoic acid or glycolic acid has a satisfactory effect. The latter can inhibit the oxidation of hydroquinone, thus improving its penetration into the epidermis, promoting the elimination of pigment, and making keratinocytes proliferate.
2. Retinoic acid
Retinoic acid can reduce the pigmentation spots caused by photoaging, and inhibit the synthesis of tyrosine, thereby inhibiting the production of melanin. Clinically, 0.1% retinoic acid cream is mostly used for external use, twice a day, with an onset time of about 24 weeks. The side effects are erythema desquamation and some contact dermatitis. However, this adverse effect does not affect the treatment effect, and gradually disappears in the process of continuous treatment.
3. Freckle remover
It is the main component of Cornus officinalis. Freckling hormone has an inhibitory effect on the production of tyrosinase and melanin. The degree of inhibition is related to the concentration. The higher the concentration, the stronger the effect.
4. Sibai freckle removing cream
It mainly contains Tianqi, chuanxiong, peach blossom, Scutellaria baicalensis, Angelica dahurica, pearl and other traditional Chinese medicine ingredients. It has the functions of promoting blood circulation and removing blood stasis, eliminating stagnation and wind, whitening and moistening the skin, inhibiting tyrosinase activity and reducing melanogenesis. Its curative effect is better than hydroquinone. It can also block and absorb ultraviolet rays and has a sunscreen effect. A few patients may have slight erythema and pruritus, which generally does not affect the treatment. Twice a day for 2 to 6 weeks.
5. Laser therapy
Laser treatment for chloasma is only applicable when other treatment methods are ineffective. Because the effect of laser treatment for chloasma is not significant (it can cause pigmentation, scar and atrophy), the principle of selecting laser treatment is to minimize the damage to normal pigment. Chloasma can be treated with Q-switched alexandrite laser, especially for female patients, but it is easy to relapse. Nouri et al. Used Q-switched laser followed by pulse laser to destroy melanocytes and reduce epidermal melanocytes, thus achieving good results in the treatment of dermal melasma. The effect of the combination of ultra pulsed carbon dioxide laser and Q-switched alexandrite laser is better than that of Q-switched alexandrite laser alone.
The above describes several methods of freckle removal. Freckle cream is simple and fast, but when choosing freckle cream, you must pay attention to the quality of your skin. In addition, you must pay attention to the maintenance of your body. When you are in a good mood and your blood is unblocked, freckles are not easy to form, which reduces the trouble of freckle removal. If you take surgical treatment, you must go to the regular one.
By understanding the above western medical treatment methods for melasma, we can tailor the medicine to the case. With the continuous development of science and technology, people are more and more inclined to use laser technology to treat melasma, which not only saves time but also avoids pain. But for which treatment method is suitable for your symptoms, you should also listen to the advice of a professional doctor, because the doctor may know your skin condition best.
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