expert: bacteriostatic agent is a necessary measure to ensure the quality of eye drops. It is allowed to add an appropriate amount
The person in charge of the relevant departments of the State Food and Drug Administration pointed out that an appropriate amount of bacteriostatic agents, commonly known as preservatives, are allowed to be added to eye drops marketed at home and abroad, and the content is usually 1 / 10000 to 2 / 10000.
Zhang Qiang, vice chairman of the pharmaceutical professional committee of the national pharmacopoeia commission, pointed out that eye drops are sterile liquid preparations made of drugs and suitable excipients for dropping into the eyes, which can be divided into aqueous or oily solutions, suspensions or emulsions. In recent years, the standards of ophthalmic preparations in the Pharmacopoeia of the United States, the European Union and Japan are the same as those in China, which all require that ophthalmic preparations meet the requirements of sterile preparations.
Zhang Qiang introduced that according to the provisions of the Chinese pharmacopoeia in 2010, “excipients that can adjust osmotic pressure, pH value, viscosity, increase drug solubility and stability of the preparation can be added to eye drops, and bacteriostatic agents and antioxidants with appropriate concentrations can be added.”. Adding necessary bacteriostatic agents, commonly known as “preservatives”, to some drugs and cosmetics is an inevitable requirement to ensure the quality of drugs and cosmetics and the safety of the use process. In addition to eye drops, there are also many drugs containing bacteriostatic agents, such as multi dose oral liquid preparations, ear preparations, nasal administration preparations, irrigation agents and dialysates. The addition of bacteriostatic agents to multi dose eye drops is to avoid the “secondary pollution” of products by microorganisms during use, and is a necessary measure to ensure product quality.
doctor: the correct use of eye drops is the key
Professor Li Xiaoxin, director of the ophthalmology department of Peking University People’s Hospital and chairman of the ophthalmology branch of the Chinese Medical Association, pointed out that from the results of clinical use and adverse reaction monitoring for many years, no micro bacteriostatic agents contained in the eye drops were found to be harmful to the eyes, but for eye patients who need long-term use, they should strictly follow the instructions and follow the medical advice during the use process, Avoid adverse stimulation and discomfort caused by improper methods or excessive use.
In response to the public’s concern about how to protect eyes healthily and use drugs scientifically, Professor Li Xiaoxin said that eye drops should not be used at will. Many students or white-collar workers often have dry eyes. It is best to go to the hospital to understand the cause of the disease and then follow the doctor’s advice. If you are not good at using eye drops for a long time, you may delay your condition. Now the public starts to pay attention to the bacteriostatic agent of eye drops, which is a good thing. It can promote the medical community to carry out more popular science activities, combine the safety of eye drops with the general knowledge of health and eye protection, and promote the rational use of drugs by the public.
On how to use eye drops correctly, experts pointed out that when using eye drops, whether for yourself or others, you should first wash your hands. Another key point is not to let the bottle mouth touch your eyes, otherwise it will pollute the eye drops. In the process of use, the more you drop, the better. Different eye diseases have different requirements. Some people have dry and uncomfortable eyes, are eager to cure them, and often drop eye drops, or even several times an hour, On the contrary, it will aggravate the symptoms. Therefore, eye drops must be strictly in accordance with the doctor’s advice or the drug instructions, and do not drop randomly. The eye drops should be used up within about 15 days after opening. Even if they are not used up, it is recommended to throw them away to avoid reuse of eye drops contaminated by microorganisms.
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